ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Home
About
List

Nucleoside diphosphate kinase A 1

Intermolecular
Cysteine 145 and cysteine 145
A redox-regulated disulphide may form between two units of Nucleoside diphosphate kinase A 1 at cysteines 145 and 145. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
59
PDB code
1bhn
Structure name
nucleoside diphosphate kinase isoform a from bovine retina
Structure deposition date
1998-06-10
Thiol separation (Å)
5
Half-sphere exposure sum ?
56
Minimum pKa ?
11
% buried
86
Peptide A name
Nucleoside diphosphate kinase A 1
Peptide B name
Nucleoside diphosphate kinase A 1
Peptide A accession
P52174
Peptide B accession
P52174
Peptide A residue number
145
Peptide B residue number
145

Ligandability

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

If this tool was useful for finding a disulphide, please cite: